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Peer review Peer review information Nature thanks Kylie James and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Molecular modeling evaluation of the enantiomers of a novel adenylyl cyclase 2 inhibitor

The authors suggested that the neutralization of FUS-LCD by N-terminal acetylation may disturb other interactions between the molecules as well as phase separation by changing the peptide net charge from 2 to 3 119