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The presence of the bloodbrain barrier (BBB) is one of the major obstacles and strictly inhibits the delivery of therapeutic drugs into the brain

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Warr RG, Hawgood S, Buckley DI, Crisp TM, Schilling J, Benson BJ, et al

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Ray S, Saini MK

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Blinding was assessed by asking participants which order of placebo and naltrexone pretreatments they believed they received after the final dosing session at the day 1 follow-up, with Dont know a valid option

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