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PubMed , Journal of Bone and Mineral Research: The Official Journal of the American Society for Bone and Mineral Research , vol

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However, oral supplementation may be limited by: Gastrointestinal intolerance Malabsorption syndromes Nausea or reduced appetite Medication-related absorption changes IV B-complex: Bypasses gastrointestinal absorption Allows predictable uptake Can be combined with hydration and other supportive nutrients May be considered when oral options are ineffective or poorly tolerated When B-Complex IV Therapy May Be Appropriate B-complex IV therapy is not intended for routine or indefinite use