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It also inhibits the survival of cancer cells through a proapoptotic mechanism

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In the following years, studies revealed a significant decrease of complex I activity in the SN of patients with idiopathic PD [83, 84], as well as reduced activity of complexes I and IV in peripheral blood [85]

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This dysbiosis may, in turn, disrupt intestinal immunity and homeostasis, contributing to systemic inflammation and perpetuating a harmful feedback loop

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