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These pathways influence the expression of adipocyte-specific transcription factors, including PPAR, C/EBP, and SREBP, which regulate lipid metabolism and adipocyte differentiation

Oxidative stress in the RPE, induced by ROS such as hydrogen peroxide, is hypothesized to be an important driving force in the progression of this disease [16]

Access this article Similar content being viewed by others Data Availability Not applicable Abbreviations ACE2: Angiotensin-converting enzyme 2 AD: Alzheimers disease ANA: Antinuclear antibodies ANCA: Antineutrophil cytoplasmic antibodies AOSD: Adult-onset Stills disease ASD: Autism spectrum disorders BBB: Blood-brain barrier CA: Carnosic acid CFS: Chronic fatigue syndrome CNS: Central nervous system COVID-19: Coronavirus disease 2019 ED: Emergency department DSF: Disulfiram FTD: Frontotemporal dementia GPX1: Glutathione peroxidase 1 GSH: Glutathione GSTM1: Glutathione S-transferase mu 1 IIM: Idiopathic inflammatory myopathies KEAP1: Kelch-like ECH-associated protein 1 MC: Mast cell nEVs: Neuron-enriched extracellular vesicles NF-: Nuclear factor kappa beta NFL: Neurofilament light chain NLRP3: NLR family pyrin domaincontaining 3 NRF2: Nuclear factor erythroid-related factor 2 NRP1: Neuropilin-1 OCR: Oxygen consumption rate OPC: Oligodendrocyte progenitor cells POTS: Postural orthostatic tachycardia syndrome ROS: Reactive oxygen species SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2 SLE: Systemic lupus erythematosus SM: Systemic mastocytosis SOD: Superoxide dismutase SR: Coronavirus spike protein receptor THT: Thioflavin T aggregation assay References Taquet M, Geddes JR, Husain M, Luciano S, Harrison PJ (2021) 6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records

The mutual regulatory role of ferroptosis and immunotherapy in Anti-tumor therapy