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Numerous studies have demonstrated an impairment in the vascular responsiveness to endothelium-specific agents in patients with hypertension and/or siblings of patients with hypertension, 35, 36, 37, 38, 39, 40 and that these abnormalities can be corrected by the infusion of an antioxidant

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Faecalibacterium prausnitzii skews human DC to prime IL10-producing T cells through TLR2/6/JNK signaling and IL-10, IL-27, CD39, and IDO-1 induction