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As we age, NAD+ levels tend to decline, which is why it has become a focus of longevity research

By interfering with this process, FOXO4-DRI frees p53, leading to selective apoptosis of senescent cells without harming healthy ones

Additionally, tesofensine 0.5 mg increased heart rate and had side effects like nausea, dry mouth, flatulence, insomnia, and depressed mood