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The systemic impact of steroids makes them riskier, especially with long-term use

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Considering the results of PARAGON trial [28], a cohort based on inclusion-criteria, which were highlighted as the greatest predictors of cardiovascular events in patients with HFpEF (e.g., higher LVMi, E/e ratio, left atrium size or pulmonary arterial systolic pressure) may provide a better framework to detect the absolute changes in response to treatment in study designs of similar size and duration in the future

Short-term recombinant human growth hormone administration improves respiratory function in abstinent anabolic-androgenic steroid users