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Description

10.3760/cma.j.issn.2095-0160.2017.07.006 65 LiG

Cisplatin, a platinum-based chemotherapeutic agent, acts on tumorigenesis mainly by inducing DNA damage and apoptosis, to which tumors are prone to develop resistance and its main side effect is that it affects the secretion function of oral salivary glands, resulting in a series of oral-associated diseases (Dasari and Tchounwou, 2014)