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Moreover, endothelial dysfunction exacerbates myocardial ischemia-reperfusion injury by impairing microvascular perfusion and amplifying oxidative and inflammatory damage [7,21]

Both were removed from the FDA Category 2 list in April 2026 and are on the July 23 to 24, 2026 advisory agenda, but they cannot be compounded until the committee recommends them and the FDA completes rulemaking, which takes time

We found significant gut dysbiosis, with reduced phylum Firmicutes and Bacteroidetes with elevated Proteobacteria at 3 days after stroke in aged mice

KEGG enrichment analysis further revealed that these genes were broadly involved in inflammation- and immune-related pathways, including the IL-17 signaling pathway and FoxO signaling pathway ( Figure 3D )