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Reports that neurotoxic aldehydes, which are normally rapidly metabolized by aldehyde dehydrogenase in the brain, accumulate in parkinsonian substantia nigra because aldehyde dehydrogenase gene expression is significantly reduced

Plasma p-tau181 accurately predicts Alzheimers disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive decline

Cooling reduces resting oxygen consumption of most human tissue by about 6% per 1C decrease with a greater decrease in brain tissue

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