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The aim of this in vitro study is to investigate the effects on normal human dermal fibroblast synthesis of collagen I and elastin, release of transforming growth factor- (TGF-), plasminogen activator inhibitor-1 (PAI-1), matrix metalloproteinases (MMP), MMP-1 and MMP-3, and elastin degradation of collagen bioactive peptides, alone and in combination with other bioactive compounds found in two different collagen-based nutraceutical supplements previously reported to increase skin elasticity in vivo 28,29

This cardiovascular benefit may be relevant for individuals with Long COVID, as they may face increased cardiovascular risks

488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays, Nudelman R, Kocks G, Mouton B et al (2023) The Nitrosamine saga: lessons learned from five years of scrutiny

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