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Recently, Lin and colleagues showed that vitamin E could reverse the effect of the cytotoxic drug bioallethrin on human glioblastoma cells by inhibiting OS and endorsing endogenous redox defense pathways, thus obstructing the chemotherapeutic effects of the drug [105]

ROS scavengers like Nacetylcysteine and Methotrexate, which inhibit NET formation by reducing ROS formation, have shown remarkable therapy benefits in some clinical or preclinical trials (210, 211)

N.2003Non-animal origin of animal thioredoxin reductases: implications for selenocysteine evolution and evolution of protein function through carboxy-terminal extensions

138,139,140 In turn, NF-B can induce TNF expression in the context of inflammation, such as lipopolysaccharide (LPS) stimulation