expression of ascorbate-glutathione cycle The impact engineered nickel oxide nanoparticles on ascorbate glutathione in Allium cepa L. | Physiology and Molecular Biology of Plants Glutathione biosynthesis pathway and glutathione-ascorbate

Woo DH, Han K-S, Shim JW, Yoon B-E, Kim E, Bae JY, et al

Reichard GA Jr., Owen OE, Haff AC, Paul P, Bortz WM

The TME is a complex and multi-layered structure, primarily consisting of cancer cells, cancer-associated fibroblasts (CAFs), cells that suppress the immune system (such as tumor-associated macrophages [TAMs], myeloid-derived suppressor cells [MDSCs], and regulatory T cells), cells that activate the immune system (including natural killer [NK] cells, dendritic cells [DCs], and T cells), and a variety of signaling molecules [33,34,35,36]

Such phenotypic heterogeneityshaped by both intrinsic programs and extrinsic cuesunderscores the limitations of traditional binary models and highlights the need for precise classification systems