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Hormonal Recovery and System Reset While traditional SERM-based PCT (e.g., Clomid, Nolvadex) may not be necessary after HGH or IGF-1 LR3 alone, users should still support: Liver and metabolic health Insulin sensitivity restoration Endogenous IGF-1 balance Testosterone production (if steroids were included) Prolonged use of IGF-1 analogs may lead to negative feedback on GH/IGF axis and necessitate time off or tapering for hormonal normalization. Baxter, R

Injectable for cosmetic claims is anecdotal

2.7 Histopathological examination Liver and kidney tissue were fixed in 4% paraformaldehyde solution for 24 h, decalcified with a 10% dilute nitric acid solution for 3 weeks, and subsequently sectioned into 5 m slices following conventional paraffin embedding

6 Future directions and research perspectives While extensive progress has been made in understanding and utilizing curcumin for oral health, several avenues remain for future exploration to fully realize its therapeutic potential