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[Abstract] Research (Wash D C)

Chiral sulfinamide-based ligands and organocatalysts The Ellman lab applies the methods and catalysts that it develops to efficient syntheses of bioactive natural products and drug candidates

For example, the Y390-containing loop is positioned in a manner similar to our original SCF FBXO22 structure with UNC10088 C and NSD2 versus the BACH1-bound structure, suggesting that the two regions function independently to recruit substrates with minimal interference

10.2174/092986711794927694 lvarez-Barrios A, lvarez L, Garca M, Artime E, Pereiro R, Gonzlez-Iglesias H: Antioxidant Defenses in the Human Eye: A Focus on Metallothioneins