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Chen and co-workers first presented the MnO 2 -based nanoagent with both Fenton metal ion delivery and GSH exhaustion capability (Figure 1E) (Lin et al., 2018)

Upon inhalation, a muco-trapping variant of motavizumab an antibody targeting respiratory syncytial virus with improved binding decreased the fraction of fast-moving respiratory syncytial virus in mice, rat and lamb models, in an Fc-glycan-dependent manner, by ~2030-fold 77