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HCG and Trophoblast Invasion Research Research has confirmed that first-trimester human trophoblastic cells specifically extravillous cytotrophoblasts (CTBs) both express hCG/LH receptors and present an invasive phenotype, establishing an autocrine/paracrine role for hCG in regulating the trophoblast invasion that is essential for blastocyst implantation and subsequent placentation

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If this picture resonates, the next step is lab work not guesswork

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