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Non-failing (NF) samples derived from rejected donor hearts were used as controls

Based on these findings, it is hypothesized that IL-17A inhibitors may improve intestinal inflammation in PSO patients by increasing the abundance of Eubacterium_hallii_group , which promotes SCFA production while increased Parasutterella promotes hypoxanthine production and regulates BAs metabolism in patients, which in turn improves intestinal barrier function and achieves the relief of clinical symptoms

Accordingly, it scavenges reactive ROS, and regenerate vitamins C and E, and GSH in their active forms (Kucukgoncu et al., 2017)

Comparisons and related research compounds