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A radiometric assay was performed by RBC using 100M5 nM SAH as an inhibitor positive control

Based on the regulatory pathways established in various physiological and pathological conditions, we propose the following hypothesis: The lipid metabolism reprogramming that occurs in the tumor microenvironment of TC may similarly disrupt the methylation patterns of specific gene regions (such as the promoter regions of tumor suppressor genes) by interfering with the demethylation process mediated by TET proteins and the methylation process mediated by DNA methyltransferases (DNMTs)

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Further insights into the use of ALA, in combination with other compounds, in obstetrics and gynecology can be found in the review by Di Tucci et al