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Proc Natl Acad Sci U S A 102:52155220 Kirly L, Kunstler A, Holler K, Fattinger M, Juhasz C, Muller M, Gullner G, Zechmann B (2012) Sulfate supply influences compartment specific glutathione metabolism and confers enhanced resistance to tobacco mosaic virus during a hypersensitive response

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Neurodegenerative diseases are characterized by the slow, progressive loss of neuronal cells in the central nervous system (CNS) and the aggregation of misfolded proteins (Cenini et al., 2020)

Conversely, fatigue denotes an overwhelming sensation of tiredness and depleted energy levels that hinder the individuals customary activities (6)