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Cancer 122 , pages279292 (2020)

Finamore A, Palmery M, Bensehaila S, Peluso I

The best working hypothesis that can be formulated from the above data as well as from the variety of preclinical data discussed in a subsequent section is that in colon cancer, CBS mRNA and protein levels are increased in a significant proportion of patients: higher intratumoral CBS serves tumor-cell-supporting roles, which, in turn, leads to worse clinical outcomes