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Disclosure of interest: Doreen Pommeranz: Nothing to disclose

Molecular Behaviour and Research Mechanisms Interaction with intracellular signalling and signal transduction pathways Influence on gene transcription and molecular activation cascades Modulation of growth factor sensitivity in controlled in-vitro systems Relationship with mitochondrial ATP dynamics and metabolic behaviour Support of enzymatic response and pathway-driven experimental models Common Research Applications Across Europe Regenerative Cell Biology Models: Studying controlled cellular behaviour and structural response mechanisms

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You may need a supplement if you: Eat a vegetarian or vegan diet and dont consume enough foods that contain the vitamins Take heartburn medications Have had weight loss surgery Have a disease that affects your stomach lining or gut, such as IBD or Crohns disease Have or are at risk of getting age-related macular degeneration (AMD) Are older and dont get enough B vitamins through your diet In many cases, you may not need a B complex supplement, but a single B vitamin supplement