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Purpose: This test is essential for diagnosing vitamin B12 deficiency, monitoring treatment effectiveness, and understanding the underlying causes of related health conditions

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Upon loss of microbial signals, modeled by germ-free, gnotobiotic, and broad-spectrum antibiotic-treated rodents, eEANs sensed the changes in intestinal epithelial and mucosal areas in the lamina propria, relayed signals to sensory vagal afferents of the nodose ganglion and dorsal vagal complex, sympathetically activated glutaminergic neurons lateral to the paragigantocellular nucleus/rostral ventrolateral medulla (LPGi/RVLM) and downstream coeliac-superior mesenteric ganglia (CM-SMG), whereby efferent nerves reduced GI transit time

BPC-157 was originally isolated from gastric juice and has extensive published data on GI tissue protection and repair, including protection against NSAID-induced gut damage