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Curcumin, extracted from Radix curcumae, reduces the expression of COX-2, 5-lipoxygenase mRNA and protein in the hippocampal neurons of epileptic rats through the regulation of free radicals and carbon monoxide synthase and improves the anti-oxidative stress effect, hippocampal neuron damage, and cognitive function of pilocarp-induced epileptic in experimental rats (Yang et al., 2018)

9, a first NCL between segments 13 and 14 selectively produces the elongated SetCys peptide, the SEA peptide segment 12 being unreactive under the mild reductive conditions imposed by the MPAA catalyst

Microglia-specific overexpression of -synuclein leads to severe dopaminergic neurodegeneration by phagocytic exhaustion and oxidative toxicity