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Augmentation therapy for alpha-1 antitrypsin deficiency: towards a personalised approach

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491-496, May 2015, doi: 10.1097/ICO.0000000000000379

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Slow is still progress

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Down-regulation of SelF in cancer cell lines leads to up-regulation of p21 and p27 (cell cycle inhibitors) and subsequently induces a slowdown in cellular proliferation and triggers a state of growth arrest specifically in colon and liver cancer cells (205207)

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