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Additionally, they discovered that curcumin inhibits IL-1-induced activation of p38 MAPK, thereby attenuating the increased expression of MLCK and safeguarding the integrity of the intestinal epithelial barrier against translocation of bacterial LPS from the intestine into systemic circulation

30 Furthermore, these researchers also report that infusion of H 2 O 2 did not alter renal reduced nicotinamide adenine dinucleotide phosphate oxidase activity