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Current SBRT strategies infrequently generate sufficient tumor regression to enable a surgical option in LAPC patients

Alharbi et al

The results indicated that scaffold implantation helps maintain intervertebral disc height, reduces NP moisture loss, and partially restores the biomechanical function of the IVD ( In vitro and in vivo experiments demonstrated that this composite scaffold enhanced osteogenic differentiation, promoted angiogenesis, and accelerated abnormal NP degeneration, making it suitable for lumbar interbody fusion (Zhang et al., 2025b)