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Finally, given the rapid expansion of the field, relevant findings beyond the temporal scope of this review are likely to continue to emerge

Pathophysiology of erectile dysfunction: the contributions of trabecular structure to function and the role of functional antagonism

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When safety of the study participants and technological developments allow, so called biomarkers can be used to collect PD data to understand if the drug reaches the target, binds to the target and exerts its expected pharmacological activity within the dose range tested