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B12 shots supply vitamin B12 as methylcobalamin or cyanocobalamin, typically given intramuscularly into the deltoid, supporting red blood cell formation, myelin and nervous system health, and the metabolism of homocysteine, a process that can falter with vegan diets, malabsorption, or medications like metformin

In this study, adults that were either obese or overweight with one weight associated condition were randomized to get subcutaneous retatrutide at various doses or placebo for a period of 48 weeks