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10.1002/adfm.201808505 143 ZhangS.YuN.ArceR

Taken together, in vivo and in vitro data suggest that FASN is essential for cell transformation and tumor development

Furthermore, HER-2 positive breast cancer (SKBR3 and 435eB) undergoes cell cycle arrest in the G0/G1 phase [351], while HER-2 negative breast cancer (MCF-7) cells mainly undergo cell cycle arrest at the S phase [352]