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Studies indicate formulations with enhanced solubility (such as cocrystal or deep eutectic systems) may reduce skin irritation in individuals with sensitive or reactive darker skin types, making them potentially preferable for extended use in this population

On the other hand, continual monitoring of the motor status in the domestic environment (regarding baseline motor status, motor fluctuations, and benefit of treatment, among other factors) is also possible by using these technology-based tools (Ossig et al., 2016)

ncRNA networks regulate the expression of oxidative stress-related genes such as NOX4, SIRT1 and GPX4, and aberrant levels of ncRNAs alter the levels of pro-oxidant markers and antioxidant enzymes in LECs (68,79,140)