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Description

Given their myriad functions, both excess and deficiency of polyamines can lead to detrimental effects

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Retinol also boosts collagen production, essential for skin strength and elasticity

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Regulation of the G2/M transition by p53

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In doxorubicin-resistant human uterine sarcoma (MES-SA/Dx5), apigenin reduces intracellular glutathione (GSH) levels by inhibiting ATP-binding cassette subfamily B member 1 (ABCB1) [60], while in prostate cancer, it reverses doxorubicin resistance by down-regulating ABCB1 protein expression [61]

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