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7 Therapeutic strategies and clinical translation With the deepening understanding of ferroptosis mechanisms, an increasing number of molecular targets have been identified as closely associated with the pathological progression of AD

Proline dehydrogenase/proline oxidase-dependent apoptosis/autophagy may be modulated by the interconversion of glutamate, ornithine, and proline, among which proline is the key amino acid (98)

Schmidt M, Pfetzer N, Schwab M, Strauss I, Kmmerer U

Methylation is also involved in the recycling of glutathione, which is required to eliminate free radicals and harmful substances from the body