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Since it is abundant in hypothalamus, it can affect the neuronal activity and thus hypothalamo-pituitary gonadal (HPG) axis to exert its impact on female reproduction [16]

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In ApoE / mice subjected to chronic mild stress, lipid metabolism disorders, increased adipocyte hypertrophy, and reduced PPARG gene expression promote AS, while PPARG exhibits an anti-ferroptosis effect (Mao et al., 2023)

R., Bakker, J., Lesaffre, E