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B12 supplements are known to play a crucial role in maintaining healthy nerve cells, which are essential for cognitive function

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Although, fatty acid oxidation (FAO) in BAT is necessary for maintaining thermogenesis (105, 106)

At the cellular level, B12 acts as a cofactor for two critical enzymatic reactions: Methionine synthase converts homocysteine to methionine, essential for DNA methylation and synthesis Methylmalonyl-CoA mutase involved in fatty acid metabolism and myelin production By restoring adequate B12 levels, injections enable normal red blood cell maturation in the bone marrow, correcting the megaloblastic anaemia