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rather, it is one of the manifestations of protein misfolding which may result from partially folded polypeptides that fail to achieve their native stable conformation or aggregation of native protein which has less solubility [23]

Protease inhibitors manage proteases that would otherwise damage sperm proteins

Two milliliters of human intercellular retinol-binding protein (IRBP 161 180 , 1 mg/mL) and 2 mL of complete Freunds adjuvant were completely blended in a three-way pipe for 2 h until a milky liquid was obtained

Schedule: Weeks 1-4: 2mg weekly Week 5+: 4mg weekly (maintenance) This protocol reaches maintenance by week 5 and provides clinically meaningful weight loss with the mildest side effect profile