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In the aforementioned study by Hsieh and collaborators (Hsieh et al., 2017) that focused on the ischemic muscle model (achieved via removal of the femoral artery), the pro-angiogenic effects of BPC 157 are evident, given the increased expression, internalization of vascular endothelial growth factor receptor 2 (VEGFR2), and the activation of the VEGFR2-Akt-eNOS signaling pathway (Hsieh et al., 2017)

Medical disclaimer: BPC-157 is a 503A compounded peptide administered under licensed medical supervision

Active malignancy requires careful evaluation Patients with active or recent malignancy require thorough clinical evaluation before initiation

Martin, E., Zhang, A., & Campiche, R