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Through injection of -syn preformed fibrils (PFFs) into the striatum of transgenic mice, researchers demonstrated the development of Lewy pathology, nigrostriatal degeneration, and importantly expanded our understanding of cell-to-cell transmission by describing the nature of spread in neuroanatomically connected regions: this provided the first evidence that synthetic -syn PFFs alone can induce the initiation and propagation of -syn pathology in vivo (Luk et al., 2012)

The effects of smoking and zinc on the oxidative reactions of human neutrophils

Uptake of nanoparticles Senescent A549 cells (1 10 5 cells per well) were treated respectively with free Ce6, m-PCC NPs, or HK-PCC NPs (equivalent Ce6 at 10 M) for 4 h

Nano Letters, 2020, 20(11): 81418150 Hou H, Huang X, Wei G, Xu F, Wang Y, Zhou S