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elevation of the inflammatory response can include a pain response and currently prescribed omeprazole therefore advisable to check B12 status

A Herxheimer reaction is typically: Temporary Associated with starting or changing treatment Followed by gradual improvement In contrast, worsening disease may involve sustained or progressive symptoms without improvement

Punganuru, S

In this study, there was statistical benefit to adding durvalumab to first-line treatment, with patients receiving durvalumab, etoposide and platinum achieving an overall survival of 13.0 months compared to 10.3 months in the control arm ( While immunotherapies have had a fair amount of success relative to other treatment options in SCLC in the past 3 years, it is important to note that one of the many virulence factors that make SCLC difficult to target is their innate ability to avoid the surveillance of the host immune system