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For the reconstitution step itself drawing the BAC water and adding it to the vial use a larger 35 mL syringe with a 2327 gauge needle

Patients often experience sudden flushing (intense redness and heat on the face and chest), migrating urticaria (hives), severe pruritus (deep, unexplained itching), and dermatographism (a condition where lightly scratching the skin causes raised, red lines)

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Clinical examination evaluation results at the second follow-up visit (one month) showed that HL and exfoliative cheilitis had resolved entirely, GT became asymptomatic, and the coated tongue had improved and decreased in score to coated tongue Miyazaki scale 1