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Consequently, pigmentation gradually reduces, and the skin regains a brighter, more even-toned appearance

The opposite effect of CK1 in erythroid precursors and mature RBCs might be explained by the lack of the caspase-10-Bid axis in erythrocytes, which is at least partly responsible for anti-apoptotic action of CK1 in the erythroid precursors

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Latif S, Jahangeer M, Maknoon Razia D et al (2021) Dopamine in parkinsons disease