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Description

Understanding fibromyalgia as fundamentally a nervous system disorder rather than a tissue damage condition helps explain why conventional pain medications often disappoint and why peptides targeting neurological and inflammatory pathways show promise

10.1016/j.heares.2009.03.004 11 CoffinA

For DSIP specifically, the substitution is far more consequential, and the reason follows directly from the half-life: Subcutaneous absorption competes with a 24 minute clearance