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Some were on the road to recovery and release, while others will remain at the center permanently

This effect was accompanied by downregulation of RAF and RAS mRNA and protein expression, suggesting a potential combinatorial therapeutic strategy ( Effects of curcumin on endometrial cancer The development of EC is driven by a complex interplay of risk factors, including obesity, diabetes, family history, hormonal imbalances, PCOS, hormone therapy, use of intrauterine devices, and endometrial hyperplasia ( Curcumin also targets anti-apoptotic molecules such as TREK-1 to reduce cell proliferation in EC cells ( in vivo models, including NOD-SCID mice, daily intraperitoneal curcumin injections (50 mg/kg) for 30 days led to a fivefold reduction in tumor volume without observed toxicity ( Curcumin also interferes with AR signaling, which plays a role in EC pathophysiology

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(Elservier, 2001)