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These cytokines not only accelerate degradation of the cartilage matrix but also amplify the local inflammatory response via autocrine or paracrine signaling (13)

Different authors have used biophysical assays to study the interaction between oleuropein and membrane lipids [61]

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Replacement of Q residues with N residues at the polyamination sites had no impact on GSH binding affinity or GST enzymatic activity compared to that of wild-type GST