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For instance, even something as subtle as the style of attention imparted by the dam to her offspring can induce pronounced epigenetic changes to GR expression

doi: 10.3389/fonc.2020.00429 290 A phase II Study of the Glutaminase Inhibitor Telaglenastat (CB-839) in Combination With the PARP Inhibitor Talazoparib in Participants With Metastatic Castration-Resistant Prostate Cancer (2021)

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One defining characteristic of VNARs is their unusual targeting properties that allow the VNAR paratope to access and bind epitopes inaccessible to conventional biologics 23,24,25,26,27,28,29