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Of course, it is unwise to directly compare the doses given to animals and the doses given to humans, as the bodys surface area should also be taken into account when translating doses between species

However, multidimensional analysis (Fig

10.1 Genomic Analysis of Drug-Resistant Cancers Some genetic factors can confer cancer drug resistance, such as oncogene encoding growth factor receptors (GFRs), cell cycle regulators, signaling molecules, transcription factors, and apoptosis mediators (143)