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For example, senescent cells upregulate BCL2 family proteins such as BCL-XL, BCL-W 24 or MCL-1 25 to prevent intrinsic apoptosis

Effects of bardoxolone methyl on hepatic enzymes in patients with type 2 diabetes mellitus and stage 4 CKD

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In this review, we describe the central roles of mitochondria in oxidative stress, inflammation, and aging, especially mechanisms in diseases, and the current mainstream drugs targeting mitochondria