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Systematic Review and Meta-Analysis. 2025

Nov-Dec 2021;42(6):103151

In this work, we have successfully overcome these problems by establishing a design strategy inspired by Mayr's work on nucleophilic reaction kinetics

Indeed, psychological (e.g., anxiety, depression, and stress [6]), hormonal (e.g., hypogonadism, hypothyroidism, hyperprolactinemia [7]), cardiovascular (e.g., hypertension, atherosclerosis, heart failure [8]), metabolic (e.g., obesity, metabolic syndrome, diabetes, dyslipidemia, gout [9,10]), neurologic (e.g., central and peripheral neuropathies [11,12,13]) risk factors can promote the development of ED [14], or its progression from subclinical to more severe forms [15]