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Notably, individuals with IBD show a depletion of butyrate-producing bacteria and diminished colonic butyrate concentrations compared to healthy controls, underscoring the immunomodulatory potential of butyrate (Hodgkinson et al., 2023)

In addition, transgenic mice that express human catalase targeted to the mitochondria exhibited less severity of age-related OA compared to WT mice [143]

doi: 10.1007/s00284-011-9915-3 229 ZilmerMSoometsURehemaALangelU

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